In the context of suspected stroke, CT of the brain is performed mainly to exclude haemorrhage
Routinely check for subtle areas of low density
Check for the 'hyperdense artery' sign, and the 'insular ribbon' sign
In the setting of acute stroke the initial CT is often normal; the main purpose of performing a CT is to exclude intracranial haemorrhage.
Signs of acute stroke
Occasionally a CT brain acquired shortly after an acute vascular event will show subtle low density in the territorial area affected. Other important signs include the 'hyperdense artery' sign and the 'insular ribbon' sign. These signs are easily overlooked if not checked for routinely.
Dense thromboembolic material is seen filling the right middle cerebral artery (MCA)
(Same patient as image below)
Insular ribbon sign
In the context of an acute infarct, CT may demonstrate loss of clarity of the insular ribbon. This is a very subtle finding and so is easily overlooked unless checked for routinely.